Table 5.
Association of rs434434 and rs17618244 and colonic transit in IBS-C and IBS-D
| No. IBS-C | IBS-C GC24 | IBS-C GC48 | No. IBS-D | IBS-D GC24 | IBS-D GC48 | |
|---|---|---|---|---|---|---|
| rs434434 AA | 5 | 1.92 ± 0.46 | 3.40 ± 1.30 | 3 | 3.69 ± 1.14 | 5.00 ± 0 |
| GA | 23 | 2.12 ± 1.03 | 2.96 ± 1.01 | 31 | 3.02 ± 1.17 | 4.16 ± 1.05 |
| GG | 32 | 1.92 ± 0.66 | 2.95 ± 1.00 | 35 | 3.32 ± 1.26 | 4.37 ± 0.94 |
| rs17618244 AA | 1 | 1.77 | 2.86 | 1 | 3.49 | 4.91 |
| AG | 24 | 1.84 ± 0.68 | 2.92 ± 1.04 | 23 | 2.56 ± 1.16 | 3.79 ± 1.24 |
| GG | 35 | 2.11 ± 0.89 | 3.04 ± 1.03 | 44 | 3.52 ± 1.13 | 4.56 ± 0.71 |
Values are means ± SD. Association of rs17618244 with both GC24 (P = 0.005) and GC48 (P = 0.034) in the combined IBS-C and IBS-D subtypes (based on the Kruskal-Wallis test). No significant associations were detected for rs434434.