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Inhibitory effect of probenecid (100 mM in the injectate) and benzylpenicillin (100 mM in the injectate) on the remaining percentage of [3H]-methotrexate and [3H]-pemetrexed in the mouse brain at 30 minutes after the dose. Data are mean ± S.D. (n = 3∼4). *P < 0.05, compared with control.
