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Effect of TrkB and p75NTR antibodies on BDNF-mediated augmentation of intestinal LM-MP contraction induced by CCh. A selective antibody to TrkB (SC8316, 1:100) but not to p75NTR (AB1444, 1:100) receptor inhibited the augmentation of CCh-induced contraction by 10 nM BDNF. The antibodies were added at the same time as BDNF and were present during the 1-h incubation period with BDNF. Data represent the percent of contraction relative to CCh. Values are means ± SE. *P < 0.05, n = 4–5.
