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Functional intestinal changes in EpcamΔ4/Δ4 mice. A: FITC-dextran administration reveals increased intestinal permeabililty in EpcamΔ4/Δ4 compared with littermate controls. n ≥ 5 mice per group measured in triplicate. B–D: proliferation index and migration markers of BrdU-stained enterocytes. n ≥ 3 mice per group. E: representative images of BrdU-stained intestine following injection of BrdU at 4- and 24-h timepoints. *P < 0.05, bars indicate standard errors of the mean.
