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Expression levels L-FABP, VEGF, and VEGFR-2 increased in both in vivo and in vitro models with MCF-7-MEK5 cells. A. A representative RT-PCR result. B. Quantitative real-time PCR showed significant increases of L-FABP, VEGF and VEGFR-2 mRNA levels in both MCF-7-MEK5 cells and in nude mouse tumor tissues. C. WB assay showed increases of L-FABP, VEGF, and VEGFR-2 proteins. *p<0.05.
