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. 2014 Feb 11;8:36. doi: 10.3389/fncel.2014.00036

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Copyright © 2014 Edgerton and Jaeger.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Example of high frequency optical stimulation trains and brief stimulation bursts to elicit LTS bursts. (A) A 1 s 20 Hz train of IPSPs triggered by 5 ms light pulses resulted in an LTS rebound burst at varying latencies. A 20-Hz train of 50 IPSPs triggered by 5 ms light pulses consistently resulted in LTS bursts in a VM neuron. Five different trials are overlaid to illustrate the trial-to-trial variability in the LTS latency. (B) Same neuron. Paired pulses (2 ms pulses, 20 ms interval) elicited LTS rebounds for some paired stimuli. These LTS rebounds consisted of 1–3 spikes.