Fig. 5.

Time course of chemokine expression in lung after intratracheal bleomycin. Transcript and protein expression for KC (A and B), MIP-2 (C and D), and CXCL5 (E and F) at 0 h, 4 h, 24 h, and 3 and 7 days after intratracheal bleomycin instillation. Transcript and protein levels peaked at 4 h for KC and MIP and at 24 h for CXCL5. Protein expression for all 3 chemokines was minimally detectable 3 days after intratracheal bleomycin administration. Data are expressed as means ± SE of n = 6 animals in each group, *P < 0.05, **P < 0.01, and ***P < 0.001.