Figure 5.

Membrane resting potential measurements in curarized and uncurarized PND preparations treated with M. laticollaris venom. (A) The depolarizing effect caused by venom (10 µg/mL) in uncurarized preparations; (B) The lack of depolarization by d-tubocurarine (d-Tc, 5 µg/mL) after 120 min of incubation; (C) The depolarizing effect caused by venom (10 µg/mL) in preparations previously treated with d-Tc (5 µg/mL) for 10 min. Note that pretreatment with d-Tc did not prevent the depolarizing effect caused by venom. The columns are the mean ± SEM of four muscles in which six different end-plates were measured per interval; * p < 0.05 compared to t₀ (control) values in all panels.