Skip to main content
. Author manuscript; available in PMC: 2014 Mar 1.
Published in final edited form as: Epilepsia. 2013 Jan 7;54(3):471–480. doi: 10.1111/epi.12062

Figure 4.

Figure 4

A group level contrast for spike-related fMRI activation in valproate (VPA)-resistant versus VPA-responsive subjects was performed. The average and standard deviation of positive t-values within four regions of interest (ROIs, refer to Fig 2) are shown. Spike times obtained from a simultaneous EEG recording were convolved with a canonical gamma variate hemodynamic response function (HRF) with its peak 4.7 s post onset using AFNI. T-maps were produced with HRF onset aligned with spikes (0 s), before spikes (−1, −2, … s), and after spikes (+1,+2, … s).

Epilepsia © ILAE