Table 3.
Summary of available IAEP case-series.
| Number of patients | Male | Female | Age | Current smokers | Number requiring intubation | BAL eosinophils % | Patients with atopic disease/asthma included | |
|---|---|---|---|---|---|---|---|---|
| Allen et al., 1989 [23] | 4 | 3 | 1 | 34 (Mean) | Unclear | 2/4 | 42 (Mean) | No asthma |
| Umeki et al., 1992 [24] | 5 | 4 | 1 | 37.7 (Mean) | 3/5 | Unclear | 20.3 (Mean for 3 patients) | Yes |
| Ogawa et al., 1993 [21] | 5 | 5 | 0 | 28.2 (Mean) | 3/5 | Unclear | 42.4 (Mean) | Yes |
| Hayakawa et al., 1994 [20] | 13 | 9 | 4 | 37.2 (Mean) | Unclear | Unclear | 40.3 (Mean) | Yes |
| Cheon et al., 1996 [25] | 6 | 4 | 2 | 29 (Mean) | 1/5 | Unclear | Unclear | No |
| Pope-Harman et al., 1996 [11] | 15 | 9 | 6 | 28.9 (Mean) | 6/15 | 8/15 | 36.9 (Mean) | Unclear |
| Tazelaar et al., 1997 [10] | 9 | 4 | 5 | 53 (mean) | 3/9 | Unclear | 1 (Only 1 patient underwent BAL) | Yes |
| Shiota et al., 2000 [22] | 2 | 2 | 0 | 23 (Mean) | 2/2 | 0/2 | 47 (Mean) | No |
| Philit et al., 2002 [2] | 22 | 13 | 9 | 29 (Mean) | 8/22 | 8/22 | 54.4 (mean) | Yes |
| Shorr et al., 2004 [8] | 18 | 16a | 2 | 22 (Median) | 18/18 | 12/18 | 40.5 (Median) | Unclear |
| Miyazaki et al., 2007 [26] | 17 | 11 | 6 | 19 (Median) | 16/17 | 0/17 | 65 (Median) | Yes |
| Daimon et al., 2008 [27] | 29 | 14 | 15 | 26 (Mean) | Unclear | Unclear | Unclear | No |
| Uchiyama et al., 2008 [6] | 33 | 23 | 10 | 19.3 (Mean) | 32/33 | Unclear | 52.8 (Mean) | Yes |
| Rhee et al., 2013 [12] | 137 | 137a | 0 | 20 (Median) | 135/137 | 3/137 | 40 (Median) | Yes |
| Our study | 8 | 5 | 3 | 53 (Median) | 2/8 | 2/8 | 36 (Median) | No |
| Total | 323 | 259 | 64 | n/a | 229/276 | 35/223 | Range 1–54.4% | At least 8 studies |
a
Military personnel study.