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. 2014 Feb 11;8:36. doi: 10.3389/fnbeh.2014.00036

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Copyright © 2014 Zack, Featherstone, Mathewson and Fletcher.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Mean (SE) locomotor response (number of beam breaks in an electronic array per 90 min) to 0.5 mg/kg d-amphetamine on separate sessions before and after a 5-session sensitizing regimen of d-amphetamine (1.0 mg/kg; i.p. per session) in groups of Sprague Dawley rats (n = 8/group) previously exposed to 15 daily conditioning sessions with sucrose reward (10% solution) delivered under 0, 25, 50, 75, or 100% variable schedules. The conditioned stimulus was a light (120 s). Group 0 received the same number of rewards as group 100 in the absence of conditioned stimuli. ^*p < 0.05 for mean difference between group 50 and group 0 as well as group 100, based on planned comparisons.