Table 1.
Outcome of IVM cycles from literature
| Authors (year) | No. of GV oocytes |
In vitro
maturation rate (%) |
Fertilization rate (%) | Cleavage rate (%) | Clinical pregnancy rate/embryo transfer (%) |
Live birth |
|---|---|---|---|---|---|---|
| Nagy, 1996 (20) | 14 | 64 | 78 | 71 | 100 | 1 |
| Kim et al., 2000 (50) | 168 | 66.7 | 51.8 | 84.5 | - | - |
| Yoon et al., 2001 (17) | 506 | 74.3 | 72.6 | 89 | 17.6 | 9 |
| Hyun et al., 2007 (42) | 901 | 61.15 | 78.4 | Good Quality: 39.8 | - | - |
| Lim et al., 2007 (30) | 619 | 80 | 75 | 96 | 35% (mixed with in vivo matured oocytes) | - |
| Shu et al., 2007 (49) | 27.1 | 37.5 | 44.2 | 100 | 2 | - |
| Son et al., 2008 (50) | 1086 | 65.1 | 71.7 | 84.4 | 38.7 | 7ongoing pregnancy, 13 delivery |
| Son et al., 2008 (27) | 336 | 46.3 | 79.8 | 95.5 | 40.9 % (mixed with in vivo matured oocytes) |
|
| Araujo et al., 2009 (31) | 61 | 82 | 70 | 91.4 | 2 | - |
| Reichman et al., 2010 (51) | 37.2 | 35.1 | 60.0 | 20.5 | None | none |
| Escrich et al., 2011 (22) | 131 | 74.8 | 59.7 | - | - | - |
| Wiser et al., 2011 (45) | 58 | 68.5 | - | 33.8 | 30% | |
| Guzman et al., 2012 (22) | 967 | 50.8 | 63.7 | Good Quality:45.4 | 34.6 (after warming) |
3 delivery, 8 ongoing |
| Tang-Pedersen et al., 2012 (18) | 253 | 33.2 | 58.3 | 18.75 | 6.7 | 1 |