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. Author manuscript; available in PMC: 2014 Feb 11.
Published in final edited form as: J Ethnopharmacol. 2010 May 4;130(2):222–230. doi: 10.1016/j.jep.2010.03.040

Fig. 5.

Fig. 5

American ginseng-induced activation of Nrf2 in the murine heart. (A) Representatives of immunochemical staining of Nrf2 from C57BL/6J mice (n=3) 6 hours after single gavages with American ginseng extract (Am. g., 50 mg/kg). Vehicle (Veh) is saline. Red is Nrf2. Green is F-actin. Blue is nuclei. (B) Semi-quantification of Nrf2 protein expression and Q-PCR analysis of Nrf2 downstream gene expression. Semi-quantification was performed using Image-Pro Plus software as described in “Methods”. Expression of HO-1, NQO-1 and Txn-1 mRNAs was used as biomarkers to indicate Nrf2 activation in the heart. Results are fold changes relative to the control treated with vehicle. *p < 0.05 vs basal (0), n=4.