Table 2.
Nested variant of urothelial carcinoma: example of results and geographic distribution of several markers in nested variant of urothelial carcinoma taken from Lin O, Cardillo M, Dalbagni G, Linkov I, Hutchinson B, and Reuter V E. Nested variant of urothelial carcinoma: a clinicopathologic and immunohistochemical study of 12 cases. Modern Pathology 2003; 16(12): 1289–1298.
| Case | Ref. | P21 result | P21 location | P27 result | P27 location | P53 result | P53 location | EGF-R result | Bc12 result | Bc12 location | MIB-1% | MIB1 location | Other comments |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Lin et al. [7] | + | Diffuse | + | Surface | − | − | − | 20 | Diffuse | |||
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| 2 | Lin et al. [7] | + | Diffuse | + | Diffuse | − | − | − | 15 | Diffuse | |||
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| 3 | Lin et al. [7] | + | Diffuse | − | − | − | − | 35 | Diffuse | ||||
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| 4 | Lin et al.[7] | + | Diffuse | + | Surface | − | − | − | 35 | Diffuse | |||
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| 5 | Lin et al. [7] | + | Base | + | Surface | + | Base | − | + | Surface | 2 | Base | |
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| 6 | Lin et al. [7] | − | + | Surface | − | − | − | 20 | Diffuse | ||||
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| 7 | Lin et al. [7] | + | Base | + | Surface | − | − | + | Surface | 35 | Diffuse | ||
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| 8 | Lin et al. [7] | + | Base | + | Surface | − | − | − | 15 | Base | |||
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| 9 | Lin et al. [7] | − | + | Surface | + | Diffuse | − | − | 30 | Diffuse | |||
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| 10 | Lin et al. [7] | + | Diffuse | + | Surface | − | − | − | 30 | Base | |||
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| 11 | Lin et al. [7] | + | Base | + | Surface | − | − | − | 20 | Diffuse | |||
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| 12 | Lin et al. [7] | + | Base | + | Surface | + | Base | − | − | 15 | Base | ||
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| 13 | Wang et al. [11] | Not done | Not done | − | Not done | Not done | Not done | ||||||
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| 14 | Tatsura et al. [12] | Not done | Not done | Not done | Not done | Not done | Not done | Cytokeratin+ | |||||
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| 15 | Terada [13] | Not done | + | Not done | Ki-67 labeling = 15%; +cytokeratins; +EMA; α-methylacyl CoA racemase; +Ca19-9; MUC1 | ||||||||
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| 16 | Terada [13] | Not done | Not done | + | Not done | Ki-67 labeling = 30%; +cytokeratins; +EMA, +p63, +p53, +C10, +CEA, +MUC1 | |||||||
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| 17 | De Berardinis et al. [14] | Not done | Not done | Strongly+ | Not done | Ki-67 +high expression | |||||||
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| 18, 19, 20, 21, 22, 23, 24 | Cardillo et al. [15] (7 cases) | Not done | Not done | Not done | Not done | ||||||||
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| 25 | Dundar et al. [16] | Not done | +40% | +40% | Not done | Ki-67 20%; 34βE12; −PSA; −AE1 | |||||||
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| 26 | Dundar et al. [16] | Not done | +50% | +40% | Ki-67 15%; +34βE12; −PSA; −AE1 | ||||||||
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| 27 | Badoual et al. [17] | Details not available | Details not available | Details not available | Details not available | Details not available | Details not available | Details not available | Details not available | Details not available | Details not available | Details not available | Details not available |
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| 28 | Badoual et al. [17] | Details not available | Details not available | Details not available | Details not available | Details not available | Details not available | Details not available | Details not available | Details not available | Details not available | Details not available | Details not available |
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| 29 | Krishnamoorthy et al. [18] | Details not available | Details not available | Details not available | Details not available | Details not available | Details not available | Details not available | Details not available | Details not available | Details not available | Details not available | Irregular nests of tubules in lamina propria |
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| 30. | Ozdemir et al. [19] | Not done | Not done | Not done | Not done | Not done | Details not available to author | ||||||
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| 31 | Holmäng and Johansson [20] | Details not available to author | Deatials not available to author | Deatials not available to author | Deatials not available to author | Deatials not available to author | Deatials not available to author | Deatials not available to author | Deatials not available to author | Deatials not available to author | Deatials not available to author | Deatials not available to author | |
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| 32 | Ooi et al. [21] | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | |
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| 33 to 86 | Linder et al. [22] | 52 patients | Details not availabe | Details not availabe | Details not availabe | Details not availabe | Details not availabe | Details not availabe | Details not availabe | Details not availabe | Details not availabe | Details not availabe | |
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| 87 | Tripodi et al. [23] | Not done | Not done | Not done | +P63 | ||||||||
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| 88 | Cerda et al. [24] | Not done | Not done | Not done | Not done | Not done | Not done | Not done | Not done | +CK7,+CK20, +34βE12, +P63 |
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| 89 | Cerda et al. [24] | Not done | Not done | Not done | Not done | Not done | Not done | Not done | Not done | Not done | Not done | +CK7,+CK20, +34βE12, +P63 | |
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| 90 | Yildiz et al. [25] | Details unavailable | Details unavailable | Details unavailable | Details unavailable | Details unavailable | Details unavailable | ||||||
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| 91 | Pusztaszeri et al. [26] | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | |||||
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| 92 | Lau [27] | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | |
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| 93 | Stern [1] | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | |
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| 94–96 | Talbert and Young [3] | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | |
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| 97–100 | Murphy and Deana [4] | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | |
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| 101–130 | Wasco et al. [8] | CK7+ (93%); CK20+ (68%); P63+ (92%); CK903+ (92%) | |||||||||||
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| 131–134 | Young and Oliva [9] | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | |
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| 135–150 | Drew et al. [10] | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | |
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| 151 and 152 | Xiao et al. [28] | High +p53 | Both Strongly+ for 63; and High Ki-67 indices Case 1 +CK 903; +CK7 +CK20; −PSA; −prostatic acid phosphatase; Strongly +p63; +p53 40% to 50%; +Ki-6730 to Case 2 +CK903; +CK7; −PSA; −prostatic acid phosphatase; −S100; −chromogranin; +p63 30 to 40%; Focally +p53; Focally +Ki-67 |
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| 153 | Huang et al. [29] | +CK7; +CK20; +thrombomodulin; +34βE12 |
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| 154–164 | Volmar et al. [30] | 8.8% | +p53 4.2%; +P27 4.7%; |
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| 165–174 | Holmäng and Johansson [20] 10 cases | Details not available | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | |
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| 175–177 | Liedberg et al. [31] | Details not available | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | |
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| 178–200 | Cox and Epstein [32] | Details not available | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | Details not available to author | |