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. Author manuscript; available in PMC: 2014 Feb 11.
Published in final edited form as: NMR Biomed. 2011 Aug 23;25(2):379–388. doi: 10.1002/nbm.1764

Figure 5. Effect of perifosine on GPCho-phosphodiesterase.

Figure 5

1H MR spectra of MCF-7 cell lysate at the beginning and at the end of phosphodiesterase activity assay measurement. The conversion of GPCho to choline was monitored throughout the reaction time period. Representative plot of choline biosynthesis versus time from both control ( ◇ ) and treated ( ■ ) cells. The data was fit to a straight-line to obtain the rates of choline formation.