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. 2013 Autumn;12(4):695–703.

Table 1.

Cytotoxic activities of triazene analogs with LDH assay (IC50 in μM).

Compound MCF7 HepG2 PC3 HT29 Hela HL60 K562 Jurkat HUVEC Yield (%)
A 1.51 ± 0.26 1.12 ± 0.30 1.24 ± 0.20 2.82 ± 0.49 8.87 ± 2.1 2.3 ± 0.51 2.1 ± 0.70 1.2 ± 0.40 4.4 ± 1.31 85
B 1.78 ± 0.50 1.89 ± 0.78 3.29 ± 1.30 3.37 ± 1.65 4.2 ± 1.40 1.36 ± 0.34 1.13 ± 0.67 1.05 ± 0.98 3.22 ± 1.10 87
C 0.59 ± 0.12 3.33 ± 1.30 0.56 ± 0.20 2.55 ± 1.33 2.54 ± 1.20 2.62 ± 0.96 1.66 ± 0.8 1.69 ± 1.02 12.61 ± 2.80 90
D 1.45 ± 0.32 1.49 ± 0.42 1.04 ± 0.11 2.03 ± 1.05 2.39 ± 1.35 1.34 ± 0.44 1.04 ± 0.38 1.44 ± 0.71 1.14 ± 0.40 88
E 6.14 ± 1.89 4.2 ± 1.20 3 ± 1.01 8.25 ± 2.20 15.54 ± 3.01 2.81 ± 0.99 9.87 ± 2.08 4.5 ± 1.67 5.05 ± 1.80 89
F 2.17 ± 0.53 1.45 ± 0.65 7 ± 2.20 2.26 ± 1.52 6.85 ± 2.80 1.3 ± 0.50 1.66 ± 0.49 1.61 ± 0.90 4.59 ± 1.76 92
G 1.57 ± 0.34 3.94 ± 1.45 4.13 ± 1.80 9.4 ± 2.30 4.88 ± 1.50 3.4 ± 1.96 6.33 ± 2.41 5.53 ± 1.44 7.43 ± 2.10 -
TMZ 0.77 ± 0.22 2.59 ± 1.30 1.39 ± 0.69 17.24 ± 3.20 8.88 ± 2.2 3.54 ± 1.56 3.82 ± 1.60 2.07 ± 1.34 4.85 ± 1.78 -