Table 2.

Comparison of outcomes between the study groups

	Treatment Group			P value
	Dabigatran (n = 50)	Warfarin (n = 50)
D-dimer
Baseline	333.6 ± 81.4†, ‡	303.9 ± 118.1†,‡		0.147
Month 1	287.9 ± 91.7†, §	262.2 ± 69.3†, §		0.118
Month 3	164.9 ± 48.9‡, §	197.2 ± 58.6‡, §		0.003
Time-Treatment Interaction *		0.013
Prothrombin fragment F1+2
Baseline	1.8 ± 0.6†, ‡	1.6 ± 0.8†,‡		0.161
Month 1	1.5 ± 0.8†, §	1.4 ± 0.6†, §		0.450
Month 3	0.4 ± 0.2‡, §	0.8 ± 0.2‡, §		<0.001
Time-Treatment Interaction *		0.002
C Reactive Protein
Baseline	11.3 ± 12.2	7.4 ± 10.7		0.100
Month 1	5.9 ± 4.9 †	6.5 ± 7.5		0.625
Month 3	1.8±1.6 †	5.1 ± 5.0		<0.001
Time-Treatment Interaction *			0.041

* Assessed by repeated measure ANOVA models.

†, ‡, §: Statistically significant results in pairwise comparisons within groups, using Bonferroni post-hoc test.