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. Author manuscript; available in PMC: 2015 Jan 1.
Published in final edited form as: Ophthalmology. 2013 Aug 17;121(1):79–87. doi: 10.1016/j.ophtha.2013.06.049

Figure 3.

Figure 3

Bar graphs showing (A) mean levels of tissue inhibitor of metalloproteinases-1 (TIMP-1) and (B) the ratios of the amounts of neutrophil collagenase (MMP-8) and gelatinase B (MMP-9) to TIMP-1 in tears of Stevens-Johnson syndrome (SJS), ocular cicatricial pemphigoid (OCP) and healthy control (controls) eyes. (A) SJS (7 eyes), OCP (24 eyes) and controls (33 eyes) tears were assayed using a fluorimetric bead-based enzyme-linked immunosorbent assay where all values were standardized to µg of protein loaded (ng/µg protein). The P values are shown on the graph (* statistically significant, Kruskal-Wallis test). (B) MMP/TIMP-1 ratios in SJS (7 eyes), OCP (23 eyes) and controls (32 eyes) tears were calculated and compared to their controls and between disease groups (*P<0.05, **P<0.01, ***P<0.001, Kruskal-Wallis test). The error bars indicate the standard errors of the mean.