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. Author manuscript; available in PMC: 2015 Jan 1.
Published in final edited form as: Biomaterials. 2013 Oct 22;35(2):846–855. doi: 10.1016/j.biomaterials.2013.10.019

Fig. 5. Linear peptides exhibit ITC profiles similar to the branched peptides.

Fig. 5

ITC profiles for linear peptides H2K and A2K (25 µM, 0.12 molar ratio/injection) titrated into siRNA (1 µM) were studied. Similar to branched peptides, histidine-containing H2K show exothermic binding at molar ratio 0 to 1.5. In contrast, when histidines were replaced with alanines, A2K behaved similarly to K4b: only an endothermic reaction is observed.