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. Author manuscript; available in PMC: 2014 Mar 10.
Published in final edited form as: J Control Release. 2012 Nov 12;166(2):124–129. doi: 10.1016/j.jconrel.2012.11.004

Figure 1. The coacervate controls the release of HB-EGF in a steady fashion.

Figure 1

(a) Chemical structure of the PEAD. The backbone of PEAD contains aspartic acid and ethylene glycol diglyceride, connected by biodegradable ester bonds. Arginine is conjugated to provide two cationic charges per repeating unit, giving PEAD strong affinity for polyanions. (b) Confocal fluorescent imaging of fluorescein-labeled coacervate shows spherical morphology with droplet diameters of 10–500 nm. Bar = 1 μm. (c) In vitro release profile of HB-EGF from the coacervate into saline over 10 days. Bars indicate means ± SD.