Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Proposed working model of calumenin (Calu)-15. Calu-15 undergoes phosphorylation at threonine at position 73 (Thr-73) by casein kinase 2 (CK2) and then promotes its entry into the nucleus. In the nucleus, Calu-15 can activate the transcription of growth differentiation factor-15 (GDF-15) via binding to its promoter region, and then leads to the formation of filopodia, which in turn promotes cell migration
