Table 4.
Surgical characteristics and peri-operative outcomes of bowel resection stage of the liver-first approach (LFA); and survival outcomes after completion of LFA
| Reference | Patients underwent bowel resection n (%) | Bowel Resection | Survival Outcomes in patients who completed both hepatic and bowel resection stages of the LFA | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Perioperative morbidity n (%) | Perioperative mortality n (%) | Number of patients completed both stages of LFA | Median Follow-up (months) | Median OS (months) | Recurrence rate n (%) | 3-year OS (%) | 5-year OS (%) | ||
| Mentha16 | 30/35 (86) | 1/30 (3) | 0 | 30 | NR | 44 | 20/30 (68%) | 60 | 31 |
| Verhoef17 | 16/23 (70) | NR | 0 | 16 | 18 | 19 | 2/16 (13%) | 89 | 89 |
| Brouquet18 | 27/41 (66) | NR | NR | 27 | 25 | 50 | 19/27 (70%) | 79 | 39 |
| De Jong19 | 16/22a (73) | 8/16 (50) | 1/16 (6) | 18b | NR | 36 | 6/18 (33%) | 41 | NR |
| Total Percentage | 89/121 (74) | 91/121 (75) | 47/91 (52%) | ||||||
| Range | 13–70 | ||||||||
a
Excluding two patients who had a complete response of the rectal cancer after chemoradiation.
b
Survival outcomes included two patients who had a complete response of rectal cancer after chemoradiation and no bowel resection was thus performed.
OS, overall survival.