Table 4.
Intraoperative variables and postoperative complications graded using the Clavien–Dindo classification
| Single hepatectomy (n = 916) | First liver resection (n = 53) | P-value | Second live r resection (n = 53) | P-value | |
|---|---|---|---|---|---|
| Type of resection, n (%) | |||||
| Major | 746 (82%) | 25 (47%) | 0.001 | 10 (19%) | 0.003 |
| Minor | 171 (12%) | 28 (53%) | 43 (81%) | ||
| Perioperative transfusions | |||||
| Blood | 0 (0–35 units) | 0 (0–18 units) | 0.439 | 0 (0–19 units) | 0.818 |
| Fresh frozen plasma | 0 (0–22 units) | 0 (0–10 units) | 0 (0–24 units) | ||
| Platelets | 0 (0–22 units) | 0 | 0 (0–2 units) | ||
| Patients with blood production, % | 31% | 24% | 19% | ||
| 30-day mortality, n | 45 | 0 | 0 | ||
| Liver dysfunctiona, n (%) | 9 (2%) [Grade 5: 1] | 1 (2%) | 0.159 | 1 (2%) | 1.0 |
| Bleeding, n (%) | 11 (1%) [Grade 3a: 3] | – | 1.0 | 0 | 1.0 |
| Bile leak, n (%) | 55 (6%) [Grade 3a: 17] | 4 (7%) [Grade 3a: 1] | 0.551 | 2 (4%) [Grade 3a: 2] | 0.628 |
| Pulmonary complications, n (%) | 52 (6%) [Grade 3a: 2; Grade 4: 4] | 2 (4%) | 0.768 | 1 (2%) | 1.0 |
| AF/dysrhythmia, n (%) | 40 (4%) | – | 0.061 | – | 1.0 |
| Abdominal collections, n (%) | 3 (<1%) [Grade 3a: 2] | – | 0.153 | – | 1.0 |
| Wound infection, n (%) | 17 (2%) | – | 0.610 | – | 1.0 |
| Wound dehiscence, n (%) | 3 (<1%) [Grade 3b: 2] | – | 0.151 | – | 1.0 |
a
Postoperative liver dysfunction was defined using the 50–50 criteria (serum prothrombin time <50% of normal, bilirubin >50 μmol/l on postoperative day 5.45
Significant complications requiring surgical, endoscopic or radiological intervention and life-threatening complications are shown in parentheses.
AF, atrial fibrillation.