Table IV.
Incidence of hepatic laboratory abnormalities among 1054 patients in profile 1001 and profile 100524
Level of abnormality |
Patients (%) experiencing elevation in
|
|||
---|---|---|---|---|
alt | ast | alp | Bilirubin | |
>3×uln | 15.2 | 7.7 | 8.9 | 0.4 |
>5×uln | 7.4 | 3.2 | 2.3 | 0.2 |
>10×uln | 3.0 | 1.5 | 0.6 | 0 |
>20×uln | 1.6 | 0.5 | 0 | 0 |
alt = alanine aminotransferase; ast = aspartate aminotransferase; alp = alkaline phosphatase; uln = upper limit of normal.