TABLE II.
Outcomes in women with ductal carcinoma in situ (dcis) treated with breast-conserving surgery and radiation, by age at diagnosis
| Variable |
Patient group
|
p Value | |||
|---|---|---|---|---|---|
| Whole cohort (n=1607) | <45 Years (n=195) | 45–50 Years (n=281) | >50 Years (n=1131) | ||
| Local recurrence [n (%)] | |||||
| Any | 209 (13) | 48 (25) | 42 (15) | 119 (11) | <0.0001 |
| Invasive | 148 (9) | 36 (18) | 31 (11) | 81 (7) | <0.0001 |
| dcis | 61 (4) | 12 (6) | 11 (4) | 38 (3) | 0.17 |
| Local recurrence-free survival (%) | |||||
| Actuarial | |||||
| 5-Year | 91 | 84 | 90 | 93 | <0.0001 |
| 10-Year | 87 | 73 | 86 | 89 | |
| Invasive | |||||
| 5-Year | 95 | 88 | 94 | 96 | <0.0001 |
| 10-Year | 90 | 78 | 90 | 93 | |
| dcis | |||||
| 5-Year | 96 | 95 | 96 | 97 | 0.13 |
| 10-Year | 96 | 94 | 96 | 97 | |
| Contralateral breast cancer–free survival (%) | |||||
| 5-Year | 97 | 98 | 99 | 97 | 0.82 |
| 10-Year | 95 | 94 | 95 | 94 | |
| Overall survival (%) | |||||
| 5-Year | 97 | 98 | 97 | 97 | 0.002 |
| 10-Year | 91 | 91 | 95 | 89 | |