TABLE III.
Factors associated with any local recurrence: univariate and multivariate analysis, adjusted for year of diagnosis
| Variable |
Multivariate analysis
|
p Value | |
|---|---|---|---|
| hr | 95% cl | ||
| Age | |||
| <45 Years | 2.6 | 1.9, 3.7 | <0.0001 |
| 45–50 Years | 1.4 | 0.98, 2.0 | 0.06 |
| >50 Years | Reference | ||
| Multifocality | |||
| Present | 1.4 | 0.99, 1.9 | 0.06 |
| Absent | Reference | ||
| Unreported | 1.2 | 0.84, 1.7 | 0.32 |
| Margin status | |||
| Positive or unreported | 1.5 | 1.1, 2.0 | 0.01 |
| Negative | Reference | ||
| Nuclear grade | |||
| High | 1.2 | 0.9, 1.7 | 0.14 |
| Moderate or low | Reference | ||
| Unreported | 0.7 | 0.5, 1.1 | 0.15 |
| Boost | |||
| Yes | 0.8 | 0.6, 1.1 | 0.12 |
| No | Reference | ||
hr = hazard ratio; cl = confidence limits.