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. 2014 Feb 11;12(2):e1001788. doi: 10.1371/journal.pbio.1001788

Figure 3. Inhibiting Cdk1 Y15 phosphorylation affects the duration of only the first cycle.

Figure 3

(A) The period of the first three cycles from individual embryos treated with PD0166285. All periods are subtracted by the median value of the control of the same cycle to emphasize the differences. The three black lines correspond to 25, 50, and 75 percentile of the population. (B) Time courses of levels of cyclin B1, Cdk1 activity, and pY15–Cdk1 in control embryos and embryos treated with 50 µM PD0166285. (Inset) Higher magnification of pY15–Cdk1 traces from 2nd to 4th period.