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. 2014 Feb 11;9(2):e87610. doi: 10.1371/journal.pone.0087610

Figure 11. Kaplan-Meier curves of queries of Luminal A + Luminal B cases.

Figure 11

A. A query of 295 cases of luminal A and luminal B (as determined in [28] using the PAM50 gene set) from the Provisional Breast Cancer Study was performed using the 55 Gene Set. 64.1% of all cases were altered (copy number and mutations). The Logrank test p-value was 0.001196. B. The cBioPortal query was repeated using the 51 genes from the SYK microarray study [3]. 53.2% of all cases were altered (copy number and mutations). The Logrank test p-value was 0.004582. C. The cBioPortal query was repeated using 4 genes (CDH1, CTTN, SRC, and TP53). 35.6% of all cases were altered (copy number and mutations). The Logrank test p-value was 0.006403.