Figure 4.

Validation of the rejection-associated signatures using external kidney transplant study data. Validation study microarray data were generated using the GeneST 1.1 platform on 15 AR and 22 NR sample sets (BiT2). A. SAM analysis of 15 AR samples when compared with the 22 NR samples indicates a general upregulation of neutrophil specific genes, of which approximately half are statistically significant (red data points). B. A general downregulation of most lymphocyte specific genes is observed, of which approximately a third are statistically significantly downregulated (green data points).