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. 2014 Feb 11;9(2):e88508. doi: 10.1371/journal.pone.0088508

Figure 3. Effect of NaHS on mRNA expression of AC isoforms and AC activity.

Figure 3

A–B: Representative gels (A) and histogram (B) demonstrating the effect of pretreatment with NaHS (100 µM, 12 hours) attenuated the effects of HENECA (100 nM, 24 hours) on mRNA expressions of AC isoforms. C: Effect of NaHS (100 µM) on AC activity stimulated by forskolin (20 µM). D: Effect of NaHS (100 µM) on Aβ42 production in SH-SY5Y cells preincubated with AC antagonist, SQ 22536 (300 µM). Control values were adjusted to 100%. Data are given as means ± S.E.M, n = 4–6. ## p<0.01, ### p<0.001 vs Con group; +++ p<0.001 vs Forsk group, * p<0.05, ** p<0.01 vs HEN group. Con, control; HEN, HENECA; Forsk, forskolin.