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. 2014 Feb 11;9(2):e88508. doi: 10.1371/journal.pone.0088508

Figure 4. Effect of NaHS on Aβ42 production involved PKA and CREB.

Figure 4

A: Effect of HENECA (100 nM) on Aβ42 formation was abolished by a PKA inhibitor, H89 (5, 10 and 15 µM). B–C: Representative gel (B) and histogram (C) depicting that pretreatment with NaHS (100 µM, 12 hours) attenuated the effects of HENECA (100 nM, 24 hours) on phosphorylation of CREB. Control values were adjusted to 100%. Data are given as means ± S.E.M, n = 4–6. ### p<0.001 vs Con group; * p<0.05, ** p<0.01, ***p<0.001 vs HEN group. Con, control; HEN, HENECA.