Table 2. Average methylation levels of the CpG sites highly methylated in the anorexia nervosa (AN) group.
Position | AN (n = 15) | Controls (n = 36) | t (df = 49) | p | |
CpG 1 | 21 | 66.4 (12.7) | 6.6 (16.0) | −12.877*** | <.001 |
CpG 34 | 327 | 64.9 (19.8) | 16.7 (20.8) | −7.663*** | <.001 |
CpG 35 | 330 | 72.7 (14.7) | 24.3 (21.9) | −7.834*** | <.001 |
CpG 46 | 503 | 88.8(12.5) | 47.0 (24.2) | −6.334** | <.001 |
CpG 47 | 526 | 72.7(14.9) | 45.0 (22.3) | −4.417** | <.001 |
Data are means (standard deviation).
Position: relative position from the transcription start site of the oxytocin receptor (OXTR) gene.
** p<0.01, *** p<0.001.