Figure 3. K⁺ independent (NCX) and K⁺ dependent (NCKX) Na⁺/Ca²⁺ exchanger activity in DCs from gsk3^KI and gsk3^WT mice.

A,B. Representative original tracings showing [Ca²⁺]_i in Fura-2/AM loaded gsk3^WT (open diamonds) and gsk3^KI (closed circles) DCs prior to and following removal of external Na⁺ (0 Na⁺) at 0 mM K⁺ (A) and at 40 mM K⁺ (B). C,D. Arithmetic means ± SEM of the peak (left) and slope (right) values of [Ca²⁺]_i increase following removal of external Na⁺ at 0 mM K⁺ (C, n = 95–129) and at 40 mM K⁺ (D, n = 27–34) in gsk3^WT DCs (white bars) and gsk3^KI DCs (black bars). *(p<0.05), ***(p<0.001), unpaired t-test.