Table 2. Univariate correlation (left columns) and multiple linear regression (right columns) determining predictors of log₁₀ CSF NFL in HIV-infected neuroasymptomatic patients with and without antiretroviral treatment.

		Univariate		Multivariate
Variable	N	Std β (r)	P	Std βadj	Padj
No treatment
Age	200	0.35	<0.001	0.26	<0.001
Blood CD4*	200	0.43	<0.001	0.36	<0.001
CSF neopterin	188	0.31	<0.001	0.23	<0.001
Log CSF WBC	200	−0.27	<0.001	−0.17	0.009
Albumin ratio	200	0.33	<0.001	0.33	<0.001
Log plasma VL	198	0.29	<0.001	NS	NS
Log CSF VL	199	−0.036	0.62	NS	NS
Treated-suppressed
Age	85	0.66	<0.001	0.57	<0.001
Blood CD4*	85	0.089	0.42	NS	NS
CSF neopterin	77	0.062	0.59	NS	NS
Log CSF WBC	85	−0.051	0.65	NS	NS
Albumin ratio	85	0.4	<0.001	0.26	0.004
Log pre ART plasma VL	63	0.16	0.23	0.23	0.013
Log pre ART CSF VL	46	−0.31	0.23	NS	NS
Log CSF VL	85	−0.091	0.41	NS	NS
Nadir CD4*	61	0.023	0.023	NS	NS

*CD4+ T-cell count was inverse transformed (1/(CD4+45·3) NS = Not significant.