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. 2014 Feb 11;9(2):e88703. doi: 10.1371/journal.pone.0088703

Table 1. Transgenic/mutant mice used in the studies.

Strain name Strain description
Fcer1g-null lack all activating but express inhibitory FcγRIIB
Fcer1α-null lack activating FcγRI only but express all other FcγRs
Fcgr2b-null Lack inhibitory FcγRIIB but express all activating FcγRs
Fcgr3-null lack activating FcγRIII only but express all other FcγRs
Fcgr4-null lack activating FcγRIV only but express all other FcγRs
Osteopetrotic mice mutant mice (op/op), devoid of colony stimulating factor 1, are macrophage and microglia deficient
C3-null lack complement component C3
B4galnt1-null express only simple gangliosides GM3 and GD3, but not complex gangliosides GM1, GD1a, GD1b or GT1b [50]
St8sia1-null over-expresses a-series gangliosides, particularly GM1 and GD1a and do not express b-series gangliosides GD3, GD2, GD1b, and GT1b [51]

FcγRs  =  Fcγ receptors.