Fig. 2.

Effect of renal denervation in old and young female SHR. A: effect on MAP. MAP was measured in young (4 mo, n = 12) and old (18–20 mo, n = 12) female SHR that were either were right uninephrectomized (UNX) or UNX + renal denervated. RD, renal denervation. Data are presented as means ± SE. *P < 0.01 compared with old females of same treatment; §P < 0.05 compared with sham rats of each age. B: renal norepinephrine (NE) levels in sham and renal denervated rats. After the measurement of MAP, rats were anesthetized, and kidneys were removed for measurement of NE by liquid chromatography/mass spectroscopy. Data are presented as means ± SE. *P < 0.01 compared with sham rats.