Table 1.

Response to adrenergic agonists in young female control or blockade-treated young and old female SHR

	Phenylephrine		Isoproterenol
	ΔMAP, mmHg	ΔHR, beats/min	ΔMAP, mmHg	ΔHR, beats/min
Young female control (n = 3)	1 ± 8	36 ± 31	−15 ± 7	47 ± 10
Young female + blockade (n = 6/group)	1 ± 2	−7 ± 13	3 ± 3	6 ± 7
Old female + blockade (n = 6/group)	4 ± 2	−6 ± 4	3 ± 2	8 ± 4

Values are means ± SE; n, number of rats. SHR, spontaneously hypertensive rats; MAP, mean arterial pressure; HR, heart rate.