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. 2014 Jan 27;5:3094. doi: 10.1038/ncomms4094

Table 3. Mean shrinkage rates of GDP MTs.

  ATP (μM) Fast (plus) end (nm s−1±s.e.m. (n)) Slow (minus) end (nm s−1±s.e.m. (n))
A-lattice (Mal3FL) 0 10.68±0.30 (5) 2.78±0.42 (5)
B-lattice 0 2.68±0.73 (5) 0.34±0.13 (5)
B-lattice 1 55.14±5.12 (5) 7.06±2.82 (5)

Mean shrinkage rates of GDP MTs held in a rigor kinesin clamp were compared before and after the release of the clamp by addition of 1 μM ATP. The shrinkage at the plus end was 29 times faster in the A-lattice enriched microtubules and significantly different from the B-lattice (t-test, P<0.0001). The slow ends of A-lattice-enriched MTs also shrank significantly faster than in the B-lattice MTs by 8 times (t-test with Welch’s correction for unequal variances, P=0.0054).