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. 2014 Jan 21;20(3):724–737. doi: 10.3748/wjg.v20.i3.724

Table 4.

Whey protein components and its basic properties

Whey components Concentration (g/L) % of Whey Protein Molecular weight (kDa) Number of amino acids residues Biological properties Recommendation grade against Helicobacter1
β-Lactoglobulin 1.3 50%-55% 18277 162 Source of essential and branched chain amino acids -
α-Lactalbumin 1.2 20%-25% 14175 123 Primary protein found in human breast milk D
Source of essential and branched chain amino acids
Immunoglobulins(A, B and C) 0.7 10%-15% 25000 (light chain) + 50000-70000 (heavy chain) - Primary protein found in colostrum Immune modulating benefits D
Lactoferrin 0.1 1%-2% 80000 700 Antioxidant A
Antibacterial, antiviral, and antifungal
Promotes growth of beneficial bacteria
Naturally occurs in breast milk, tears, saliva, bile, blood, and mucus
Lactoperoxidase 0.03 0.50% 70000 612 Inhibits growth of bacteria -
Bovine Serum Albumin 0.4 5%-10% 66267 582 Source of essential amino acids -
Large protein
Glycomacropeptide 1.2 10%-15% 6700 64 Source of branched chain amino acids D
Lacks the aromatic amino acids phenylalanine, tryptophan and tyrosine
1

Grades of recommendations: A: At least one meta-analysis, systematic review, or RCT rated as 1++ and directly applicable to the target population or A systematic review of RCTs or a body of evidence consisting principally of studies rated as 1++ directly applicable to the target population and demonstrating overall consistency of results; B: A body of evidence including studies rated as 2++ directly applicable to the target population and demonstrating overall consistency of results or Extrapolated evidence from studies rated as 1++ or 1+; C: A body of evidence including studies rated as 2+ directly applicable to the target population and demonstrating overall consistency of results or Extrapolated evidence from studies rated as 2++; D: Evidence level 3 or 4 or Extrapolated evidence from studies rated as 2+.