Table 4.
Whey components | Concentration (g/L) | % of Whey Protein | Molecular weight (kDa) | Number of amino acids residues | Biological properties | Recommendation grade against Helicobacter1 |
β-Lactoglobulin | 1.3 | 50%-55% | 18277 | 162 | Source of essential and branched chain amino acids | - |
α-Lactalbumin | 1.2 | 20%-25% | 14175 | 123 | Primary protein found in human breast milk | D |
Source of essential and branched chain amino acids | ||||||
Immunoglobulins(A, B and C) | 0.7 | 10%-15% | 25000 (light chain) + 50000-70000 (heavy chain) | - | Primary protein found in colostrum Immune modulating benefits | D |
Lactoferrin | 0.1 | 1%-2% | 80000 | 700 | Antioxidant | A |
Antibacterial, antiviral, and antifungal | ||||||
Promotes growth of beneficial bacteria | ||||||
Naturally occurs in breast milk, tears, saliva, bile, blood, and mucus | ||||||
Lactoperoxidase | 0.03 | 0.50% | 70000 | 612 | Inhibits growth of bacteria | - |
Bovine Serum Albumin | 0.4 | 5%-10% | 66267 | 582 | Source of essential amino acids | - |
Large protein | ||||||
Glycomacropeptide | 1.2 | 10%-15% | 6700 | 64 | Source of branched chain amino acids | D |
Lacks the aromatic amino acids phenylalanine, tryptophan and tyrosine |
Grades of recommendations: A: At least one meta-analysis, systematic review, or RCT rated as 1++ and directly applicable to the target population or A systematic review of RCTs or a body of evidence consisting principally of studies rated as 1++ directly applicable to the target population and demonstrating overall consistency of results; B: A body of evidence including studies rated as 2++ directly applicable to the target population and demonstrating overall consistency of results or Extrapolated evidence from studies rated as 1++ or 1+; C: A body of evidence including studies rated as 2+ directly applicable to the target population and demonstrating overall consistency of results or Extrapolated evidence from studies rated as 2++; D: Evidence level 3 or 4 or Extrapolated evidence from studies rated as 2+.