Fig. 2.

The incidence rates of particular variants in codon 148 of CDKN2A gene in various neoplasms, found in the Polish population. The occurrence of adenine instead of guanine in codon 148 is associated with the change of the coded amino acid - alanine (CGG) - to threonine (CGA).

n- the number of studied subjects controls - a control group for the Polish population, consisting of 500 newborns and 710 adult; „significant” - designates a group of neoplasms, in which the percent of the threonine-encoding variant was statistically significantly higher than in the control population; „not significant” - designates a group of neoplasms in which the distribution of incidence of the threonine-encoding variant is not different from that in the general population.

Based on the study by Dębniak et al. 2006 [31].