Table 6.

Parameters for MLCK and MLCP kinetics

Parameter	Value	Unit
k 1 CaM	2.8 × 106	mM−1·s−1
k −1 CaM	6	s−1
k 2 CaM	108	mM−1·s−1
k −2 CaM	800	s−1
k 3 CaM	2.8 × 106	mM−1·s−1
k −3 CaM	6	s−1
k 4 CaM	108	mM−1·s−1
k −4 CaM	800	s−1
k 5 CaM	109	mM−1·s−1
k −5 CaM	20	s−1
k 6 CaM	1.25 × 107	mM−1·s−1
k −6 CaM	5	s−1
k 7 CaM	109	mM−1·s−1
k −7 CaM	1	s−1
[CaM]tot	10 × 10−3	mM
[MLCK]tot	2 × 10−3	mM
[MLCP]tot	2 × 10−3	mM
[RhoK]	30 × 10−6	mM
kcat/k+MLCP	0.33 × 106	mM−1
k MLCK Myo	0.537	s−1
k MLCP Myo	1.62	s−1
k 3 Myo	1.8	s−1
k 4 Myo	0.1	s−1
k 7 Myo	0.045	s−1
[Myo]tot	30 × 10−3	mM

See mathematical model for definitions.