Figure 2.

A = Panoramic radiograph of a woman with breast cancer treated with zoledronate ‎who presented with a painful tooth # 37‎‏.‏

B = Panoramic radiograph after 7 months, showing non healing extraction site in the left ‎posterior mandible, absence of bone remodeling and sclerotic bone changes of the body of the ‎mandible‏.‏

C = Panoramic radiograph after 9 months demonstrates a nonhealing extraction site in the left ‎posterior mandible with progressive sclerosis of the left body and angle of the mandible with ‎encroachment on the left mandibular canal‏.‏

D = Panoramic radiograph after 19 months with intervening curettage, demonstrates progression ‎of sclerosis to pathologic fracture of the mandible.