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View full-text article in PMC

. Author manuscript; available in PMC: 2014 Feb 12.

Published in final edited form as: J Addict Res Ther. 2013 May 14;Suppl 7:007.

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Copyright: © 2013 Li Z, et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

PMC Copyright notice

Interactive effects of OPRM1, OPRD1, and OPRK1 variants on alcohol, cocaine, or opioid dependence.

Two-locus marker-based gene-gene interaction analysis was performed using the program Pattern Examiner to indentify marker patterns which were significantly more frequent in cases than in controls. 12 significant patterns in the alcohol dependence (AD) dataset, four significant patterns in the cocaine dependence (CD) dataset, and 18 significant patterns in the opioid dependence (OD) dataset were identified.