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Topographic views of human MDF stained with (A) 1% Alcian blue (pH 2.5) and (B) hematoxylin and eosin. MDF were identified as focal lesions characterized by loss of Alcian blue staining, attributable to the loss of mucin, as compared with the surrounding normal crypts. AB, Alcian blue; HE, hematoxylin and eosin.
