Table 1.
Body and kidney weights of Sham, 2K1C and 2K1C-sildenafil treated mice 28 days after renal artery clipping
| Parameters | Sham (n = 8) | 2K1C (n = 10) | 2K1C sildenafil (n = 8) |
|---|---|---|---|
| Body weight (g) |
26 ± 0.5 |
24 ± 0.4* |
26 ± 0.3# |
| Clipped kidney dry weight/body weight (mg/g) |
1.63 ± 0.07 |
0.96 ± 0.17** |
1.5 ± 0.04# |
| Nonclipped kidney dry weight/body weight (mg/g) |
1.78 ± 0.04 |
2.02 ± 0.06* |
1.77 ± 0.05# |
| Clipped kidney weight/nonclipped kidney weight ratio |
0.91 ± 0.04 |
0.54 ± 0.09** |
0.78 ± 0.06# |
| Kidney cell viability (%) | 99 ± 0.13 | 94 ± 1.5** | 98 ± 0.6# |
Values are the means ± SEM. *p < 0.05 and **p < 0.01 compared with Sham group; #p < 0.05 compared with 2K1C group.