Skip to main content
. Author manuscript; available in PMC: 2014 Dec 15.
Published in final edited form as: Cancer Res. 2013 Oct 31;73(24):7189–7198. doi: 10.1158/0008-5472.CAN-12-4174

Table 1. Summary of maximum toxicities related to anti-OX40 at all dose levels.

Patients with multiple instances of the same toxicity were tabulated once with the highest grade for that toxicity.

Adverse events
Toxicity Grade 1 Grade 2 Grade 3 Grade 4
Lymphopenia 3 10 6 1
Fatigue 7 12
Rash/Skin Changes 4 6
Pruritis 5 1
Fever/Chills 11 2
Splenomegaly 7
Arthralgias/Myalgias 5 5
Nausea/Vomiting 4 3
Increased AST, ALT or alkaline phosphatase 2 1
Anemia 1 8