Table 2.
Predictors of Antiretroviral Therapy Initiation
| Variable | Adjusteda HR (95% CI) | P for Trend |
|---|---|---|
| Baseline variables | ||
| Year at baseline >2000 | 1.22 (1.16–1.29) | <.001 |
| Race | ||
| White non-Hispanic | Referent | .002b |
| Black non-Hispanic | 0.90 (.85–.95) | |
| Hispanic | 0.89 (.82–.97) | |
| Other | 0.95 (.81–1.11) | |
| Drug abuse condition | 0.85 (.81–.90) | <.001 |
| Time-dependent variables | ||
| Current CD4, cells/µL | ||
| <50 | 3.37 (2.81–4.02) | <.001 |
| 50–199 | 3.38 (2.93–3.89) | |
| 200–349 | 2.54 (2.25–2.86) | |
| 350–499 | 1.56 (1.40–1.74) | |
| ≥500 | Referent | |
| Current HIV RNA, copies/mL | ||
| ≤400 | Referent | <.001 |
| 401–10 000 | 0.91 (.83–1.00) | |
| 10 001–100 000 | 1.05 (.95–1.16) | |
| >100 000 | 1.20 (1.07–1.35) | |
| AIDS-defining condition | 1.40 (1.31–1.50) | <.001 |
Patients missing values at initiation: current CD4 (33 [0.5%]); current HIV RNA (13 [0.2%]).
Abbreviations: CI, confidence interval; HIV, human immunodeficiency virus; HR, hazard ratio.
a The adjusted model contains all the variables listed in the table, as well as baseline measures of the time-dependent variables for purposes of creating stabilized inverse probability weights.
b Type 3 P value assessing race categories as a whole, testing whether any of the β estimates are significantly different from each other.