Table 2.
Relationship between metastasis and Twist1, Twist2, E-cad, MMP-2 and MMP-9 expression in HCC (chi-square test)
| Variant | Tissue samples | Chi-square test | P-value | ||
|---|---|---|---|---|---|
| Metastasis (−) | Metastasis (+) | ||||
| Twist1 (nuclear) | Negative | 39 | 25 | 9.871 | 0.002* |
| Positive | 9 | 24 | |||
| Twist1 (cytoplasm) | Negative | 27 | 19 | 2.970 | 0.085 |
| Positive | 21 | 30 | |||
| Twist2 | Negative | 24 | 21 | 0.497 | 0.481 |
| Positive | 24 | 28 | |||
| E-cadherin | Negative | 21 | 27 | 1.25 | 0.264 |
| Positive | 27 | 22 | |||
| MMP2 | Negative | 12 | 15 | 0.38 | 0.537 |
| Positive | 36 | 34 | |||
| MMP9 | Negative | 20 | 16 | 0.844 | 0.358 |
| Positive | 28 | 33 |
Significant difference.