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Immunohistochemical staining of p53, Bax, and Bcl-2 in the primary tumor tissues. Biopsies of primary lesion from patients in groups I, II and III were taken 3 days before the treatment (pre-treatment) and 3 days after the treatment (post-treatment), and processed for immunoreactivity to (A) p53, (B) Bax, and (C) Bcl-2. The p53 staining post-treatment is presented at ×100 magnification, whereas all other panels are presented at ×400 magnification.
