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. Author manuscript; available in PMC: 2014 Feb 12.
Published in final edited form as: Methods Mol Biol. 2010;674:179–193. doi: 10.1007/978-1-60761-854-6_11

Figure 5. Data-driven motif match threshold selection.

Figure 5

Shown is a sensitivity vs. specificity curve for the PPARγ motif used as a classifier of bound and unbound sequences. A threshold selected to maximize sensitivity while keeping the false-discovery rate below 20% recovers 56% of the bound sequences.